During the White House’s press conference this week, at which President Trump called the Tylenol's and-in-law drug drug as a possible reason for increasing the level of autismIN He did not shoot a word Pregnant women are called up “Fight like hell” so as not to accept it.
But outside these comments in the Roosevelt room, during which Trump himself admitted: “I am not so careful with what I am saying,” the discussion of the general fever and the role of pain relief during pregnancy are much more nuanced.
What does the study of Tylenol actually say during pregnancy
Doctors, researchers in the very studies mentioned in support of Trump’s position, and even other members of the presidential administration are largely combined in several key facts: unprocessed fever during pregnancy is a real risk for the fetus, ascetaminophene (active Tylenol ingredient) remains the safest medicine to handle them, and any pregnant woman, seeking the advice on this issue, follows this issue. Take a doctor.
“Everything we must ask for a medical profession [is] To actually weigh the risks and advantages for women, with women, and be careful with the chronic use of painkillers, ”said Dr. bit ritzprofessor of epidemiology UCLA, who is co -author paper published last month that The White House was quoted as evidence of the connection between Tylenol and Autism.
Ritz said that this was incorrectly interpreted.
The conclusion of the article, which considered existing studies on this topic, consisted in the fact that the relationship between the use of acetaminophen during pregnancy and later diagnoses of disorders of the nervous system development in children was strong enough to earn the examination of doctors when determining how to treat fever or pain during pregnancy. According to her, the group did not determine the causal relationship between the drug and autism or suggested that in general to ban the drug.
“Looking at all these studies, yes, there is a risk,” said Ritz. “This is not very large, but it is, but the risk is more observed among regular Tylenol users. This is not a woman who has a heat and takes three tiles. ”
“There is always a weighing of risks and advantages, and the fever in women is also not very good. … No need to take any painkillers when you have severe pain or chronic pain is also very cruel, ”she said. “We must all be interested in helping here, making the right decisions without accusing the victim and not putting everything on a separate woman.”
Its co -author, epidemiologist of the University of Massachusetts Ann Bauer, made similar statements.
“We recommend reasonable use – the lowest effective dose [for] The shortest period of time under medical leadership and supervision adapted to a person ”, Bauer told the news Politician.
Confused recommendations of the administration
Ultimately, this is also recommended by the administration.
A letter The fact that the United States, the administrator of the sanitary supervision of the quality of food and medicine, Dr. Marty Makari, sent to doctors this week, clearly made it clear that the “causal relationship” between autism and acetaminophen “was not established, and opposite studies were conducted in the scientific literature.”
Further, it was recommended that the clinicians think about limiting their use of acetaminophene for ordinary fever with a low degree during pregnancy, noting that medical councils “should also be balanced with the fact that acetaminophene is the safest overpanding alternative during pregnancy among all analgists and anti -Operates.” (Analgesic is an analgesic; antiframotics reduces fever.)
Unprocessed fever during pregnancy is associated with higher indicators of congenital defects, especially indicators of the heart, brain and spinal cord; premature birth; low birth weight; Unproductive disorders, including autism; And the death of the fetus, said Dr. E. Nicole Til, associate professor of the Mother Medicine Department of California University at San Diego.
“The letter of FDA, although much more nuanced than the president’s comments on this issue, still gives too much weight for conclusions from poorly designed research,” she said.
She said that she would continue to prescribe acetaminophen to pregnant patients who need to treat fever or severe pain, since he has the lowest known risk during pregnancy.
Are there other drugs that reduce painkillers and reducing fever that can be used during pregnancy?
Non -steroidal anti -inflammatory drugs, such as Ibuprofen (frequently sold as Advil) or intraxen (frequently sold as Aleve) are associated with problems with the development of blood vessels and kidneys, as well as oligohydramnios, in which there is not enough amniotic fluid to support healthy pregnancy. According to Tila, aspirin increases the risk of bleeding complications and drugs – which can relieve pain, but not fever – risk both for the mother and babies.
She referred to statement From the American College of obstetricians and gynecologists, it was noted that two decades of research on this issue could not find a causal relationship between acetaminophen and autism.
“Acetaminophene is one of the few options available to pregnant patients to treat pain and fever that may be harmful to pregnant women when they are not treated,” said Substris and President of gynecologists, Dr. Stephen J. Fleischman. statementField
The group too marked These are reviews in 2015 And 2017 From the FDA and the Maternal Ftat medicine society, respectively, there were no risks associated with the proper use of the drug during pregnancy.
How to navigate
Nevertheless, mixed messages from the Trump administration about Tylenol will probably continue.
The Ministry of Health and Social Services this week is reposed Twit of 2017 From the Tylenol brand account, it says: “We do not really recommend using which of our products during pregnancy.”
The press secretary of Kenvue, a company owned by Tylenol, said that the post was withdrawn from context and incomplete.
“In accordance with the rules, our label clearly states:“ If pregnant or breastfeeding, ask a medical worker before use, ”said Melissa Witt in an email. “We do not give recommendations for the adoption of any drugs during pregnancy, because this is the work of the supplier of medical services.”
Vice -President JD Vance proposed a similar guide this week.
“My guide to pregnant women would be very simple, which follows your doctor. Right?” Vance said in interview With the socket of the newspaper after the press conference of Trump. “Talk to your doctor about these things.”
