Transcriptomics
Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets
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To evaluate technical performance, we first focused on data from the Xenium (10x Genomics) and CosMx SMI (Bruker Spatial Biology) ...
Multimodal learning enables chat-based exploration of single-cell data
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Multimodal training data of paired transcriptomes and text To establish a large training dataset of transcriptomes and their matched textual ...
KATMAP infers splicing factor activity and regulatory targets from knockdown data
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Selecting the knockdown experiments We selected ENCODE knockdown RNA-seq experiments for proteins annotated as SFs24 and which had a good ...
High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes
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Ståhl, P. L. et al. Visualization and analysis of gene expression in tissue sections by spatial transcriptomics. Science 353, 78–82 ...
Four game-changing immunology tools to watch
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Magnified view of a brain organoid with fluorescent labeling of various cell types.Photo: Thomas Hartung, Johns Hopkins University. Advanced tools ...
