Stem-cell biotechnology

Programmable promoter editing for precise control of transgene expression

Programmable promoter editing for precise control of transgene expression

kakameo

Domingo, J. et al. Nonlinear transcriptional responses to gradual modulation of transcription factor dosage. Preprint at bioRxiv https://doi.org/10.1101/2024.03.01.582837, peer reviewed ...

Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells

Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells

kakameo

Li, W. et al. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature 490, 407–411 (2012). Article  CAS  PubMed  ...