Stem-cell biotechnology

Programmable promoter editing for precise control of transgene expression
kakameo
Domingo, J. et al. Nonlinear transcriptional responses to gradual modulation of transcription factor dosage. Preprint at bioRxiv https://doi.org/10.1101/2024.03.01.582837, peer reviewed ...

Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells
kakameo
Li, W. et al. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature 490, 407–411 (2012). Article CAS PubMed ...