Biotechnology
AlphaDIA enables DIA transfer learning for feature-free proteomics
Calibration and optimization of retention time, ion mobility and m/z During search, AlphaDIA calibrates library properties such as retention time, ...
Integrated epigenetic and genetic programming of primary human T cells
T cell isolation and culture Human peripheral blood Leukopaks enriched for peripheral blood mononuclear cells (PBMCs) from deidentified healthy donors ...
Eye implant and high-tech glasses restore vision lost to age
A study participant checks her reading after receiving a retinal implant. Moorfields Eye Hospital People with severe vision The Lost ...
Jona Health Review: Microbiome Decoder for Health Conditions
Look, there's nothing better than starting your day by pooping on a little paper hammock attached to the toilet seat ...
Tumor-on-chip models of CAR-T cell therapy
Liu, H. et al. Nat. Biotechnology. https://doi.org/10.1038/s41587-025-02845-z (2025). Maulana, T.I. etc. Cell Stem cell 31989–1002.e9 (2024). Article CAS PubMed Google ...
A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors
Newick, K., O’Brien, S., Moon, E. & Albelda, S. M. CAR T cell therapy for solid tumors. Annu Rev. Med. ...
Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic
Stratton, M. R., Campbell, P. J. & Futreal, P. A. The cancer genome. Nature 458, 719–724 (2009). Article CAS PubMed ...
Predicting functions of uncharacterized gene products from microbial communities
Armet, A. M. et al. Rethinking healthy eating in light of the gut microbiome. Cell Host Microbe 30, 764–785 (2022). ...
Programmable promoter editing for precise control of transgene expression
Domingo, J. et al. Nonlinear transcriptional responses to gradual modulation of transcription factor dosage. Preprint at bioRxiv https://doi.org/10.1101/2024.03.01.582837, peer reviewed ...
Engineered pattern recognition receptors enhance broad-spectrum plant resistance
RLP23 transfer enhances tomato resistance to multiple pathogens The Arabidopsis receptor RLP23 recognizes the conserved immunogenic epitope nlp20, which is ...
