Biomedical Engineering/Biotechnology

A trimodal protein language model enables advanced protein searches

A trimodal protein language model enables advanced protein searches

kakameo

Altschul, S. F. et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. ...

Discovery and protein language model-guided design of hyperactive transposases

Discovery and protein language model-guided design of hyperactive transposases

kakameo

Retrieval of PiggyBac transposons Complete PiggyBac transposon sequences were gathered from all available eukaryotic genomes in the NCBI database35 (31,565 ...

Detecting and quantifying circular RNAs in terabyte-scale RNA-seq datasets with CIRI3

Detecting and quantifying circular RNAs in terabyte-scale RNA-seq datasets with CIRI3

kakameo

Circular RNAs (circRNAs) are a unique class of noncoding RNA molecules characterized by their covalent circular structure1. Recent studies have ...

Derivation of embryonic stem cells across avian species

Derivation of embryonic stem cells across avian species

kakameo

Optimizing chicken ES cell culture conditions To develop culture conditions for deriving chicken ES cells, we isolated blastodermal cells from ...

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