Bioinformatics

Scaling DNA synthesis with a microchip-based massively parallel synthesis system
Guarini, S. et al. Various cholinergic routes participate in an improvement caused by CCK-8, and ActH- (1–24) in a massive ...

A trimodal protein language model enables advanced protein searches
Altschul, S. F. et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. ...

Discovery and protein language model-guided design of hyperactive transposases
Retrieval of PiggyBac transposons Complete PiggyBac transposon sequences were gathered from all available eukaryotic genomes in the NCBI database35 (31,565 ...

Detecting and quantifying circular RNAs in terabyte-scale RNA-seq datasets with CIRI3
Circular RNAs (circRNAs) are a unique class of noncoding RNA molecules characterized by their covalent circular structure1. Recent studies have ...

Derivation of embryonic stem cells across avian species
Optimizing chicken ES cell culture conditions To develop culture conditions for deriving chicken ES cells, we isolated blastodermal cells from ...






