Agriculture
KATMAP infers splicing factor activity and regulatory targets from knockdown data
Selecting the knockdown experiments We selected ENCODE knockdown RNA-seq experiments for proteins annotated as SFs24 and which had a good ...
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin
Cho, J. S., Kim, G. B., Eun, H., Moon, C. W. & Lee, S. Y. Designing microbial cell factories for ...
Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity
Palmer, S., Albergante, L., Blackburn, C. C. & Newman, T. J. Thymic involution and rising disease incidence with age. Proc. ...
High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes
Ståhl, P. L. et al. Visualization and analysis of gene expression in tissue sections by spatial transcriptomics. Science 353, 78–82 ...
A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels
Immunofluorescence analysis of apical–basal polarity and proliferation marker Ki67 P26N human colon organoids were grown for 2 days in BME ± ...
Selective RNA sequestration in biomolecular condensates directs cell fate transitions
P-body purification To profile P-body contents, we adapted a fluorescence-activated sorting method29,42 using a green fluorescent protein (GFP)-LSM14A expression construct ...
Zanzibar is seeing a seaweed boom. Can the women collecting it cash in?
ZANZIBAR, Tanzania. Women wander along the beaches with baskets, their colorful dresses attracting the attention of tourist cameras. The sunscreen ...
Elucidating lipid nanoparticle properties and structure through biophysical analyses
Pardi, N., Hogan, M. J., Porter, F. W. & Weissman, D. mRNA vaccines—a new era in vaccinology. Nat. Rev. Drug ...
Discovery and engineering of retrons for precise genome editing
Fichter, K. M., Setayesh, T. & Malik, P. Strategies for precise gene edits in mammalian cells. Mol. Ther. Nucleic Acids ...
Gene-edited pigs resistant to swine fever could boost animal welfare
Gene-edited pigs are resistant to classical swine fever Simon Lillico A little genetic tweaking can make pigs completely resistant to ...
