The NFL's Week 15 schedule is full of playoff implications. Among them is the AFC West matchup between Justin Herbert and the Los Angeles Chargers against Patrick Mahomes and the Kansas City Chiefs. Los Angeles is in the thick of the AFC West race, while the Chiefs need a strong finish and a lot of help to reach the postseason for the 11th straight year. Kansas City is a 5.5-point favorite and is 4-6 against the spread in its last 10 games, while Los Angeles is 3-6-1 ATS in its last 10 games and is coming off a short week and overtime no less. The Chargers won their last meeting 27–21 in Brazil on September 5.
There are a number of other good matchups on the NFL's Week 15 schedule, including Bills (-1.5) vs. Patriots, Ravens (-2.5) vs. Bengals, Packers (-2.5) vs. Broncos, Lions vs. Rams (-6) and Colts vs. Seahawks (-13.5). Before locking in any Week 15 NFL picks or NFL parlays, be sure to see NFL predictions and betting tips from SportsLine's proven computer model..
The model, which simulates every NFL game 10,000 times, costs more than $7,000 for players with $100 in top games. NFL Pick since its creation. The model enters Week 15 with a score of 50-35 on the highest-ranking samples going back to 2024. NFL Betting poking around in bookmakers and further betting sites could see strong profits.
Now the model has been searched Week 15 NFL Odds and recorded five solid best bets on the NFL. If you successfully bet on his picks, you will receive a huge payout of almost 25-1. You can see just the Week 15 NFL model picks at SportsLine..
Top NFL picks for Week 15
After simulating every game 10,000 times, the model has the Dallas Cowboys (-5.5, 47.5) high to defend against the Minnesota Vikings on Sunday Night Football.
The Cowboys are led by quarterback Dak Prescott. In 13 games this season, he has completed 69% of his passes for 3,637 yards and 26 touchdowns with 10 interceptions and a 100.2 rating. He also rushed 44 times for 138 yards (3.1 average) and two touchdowns. In a 44–30 loss to Detroit in Week 14, he completed 31 of 47 passes for 376 yards and one touchdown with two interceptions.
Bet Prescott will go over 37.5 yards on his longest completion using the latest data. DraftKings Promo Codewhich offers a $200 bonus bet if your bet wins:
The model has Dallas winning outright over 70% of the time and covering in nearly 60% of simulations in an A-rated spread pick. See which other NFL parlay picks to make here, and new users can bet the Cowboys to cover using the DraftKings promo code, which offers $200 in bonus bets if your bet wins:
How to make Week 15 NFL parlays
The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog that it says will easily cover. You can only see the model's Week 15 NFL best bets and NFL parlay at SportsLine.
What are the model's top Week 15 NFL picks, and which NFL matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 15 NFL best bets from a model on a 50-35 run on top-rated picks, and find out.
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