Computer model locks in Chargers vs. Broncos picks, score prediction

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The Denver Broncos will look to clinch the No. 1 seed in the AFC when they host the Los Angeles Chargers in Week 18 of the 2025 NFL season. The Chargers don't have much to play for other than playoff seeding, and as a result, they plan to rest Justin Herbert and other key starters. If Denver wins this game, the Broncos will earn the No. 1 seed and a first-round bye in the playoffs.

Kickoff at Mile High's Empower Stadium is set for 4:25 pm ET on CBS and Paramount+. The Broncos are 12.5-point favorites in the latest Chargers vs. Broncos odds on DraftKings, with the total set at 37.5. Before you make any choice between the Broncos and Chargers, be sure to look at the top. NFL Pick from the SportsLine projection model, which models everything NFL game 10,000 times.

Where to watch Chargers vs. Broncos on Sunday

When: Sunday, January 4
Time: 4:25 pm ET
TV: CBS
Broadcast: Paramount+
Follow the instructions: CBS Sports App

Chargers vs. Broncos Betting Preview

Chances: Broncos -12.5, over/under 37.5

Despite their stellar record, Denver is just 6-9-1 against the spread. Los Angeles is 8-7-1 ATS but had four straight coverages before losing to the Texans at home in Week 17. The Chargers are 6-9-1 in the over, while the Broncos are 7-9 in the over.

Chargers vs Broncos SGP

  • Chargers +12.5
  • More than 37.5
  • RJ Harvey, Anytime Touchdown Scorer.

Place your bet on DraftKings:

Models Chargers vs Broncos Score Prediction, Elections

The Chargers cover the spread in 58% of model simulations and win 27%, making them a +575 value underdog. Over hits in 51% of simulations.

Chargers vs. Broncos score prediction: Broncos 25, Chargers 15

Want more NFL picks in Week 18?

You've seen the model's best bets for the Los Angeles Chargers vs. Denver Broncos game. Now, get spread, total and moneyline data for every Week 18 NFL game hereall from a model that was simulated every game 10,000 times.

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