These authors contributed equally: Nobutaka Kato, Eamon Comer.
Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
Nebutaka Kato, Comer, Mika Maetani, Joshua A. Bittker, Emily. Area, Paul A. Clemmons, Michael A.
Harvard School of Public Health T.C. Chana, Boston, Massachusetts, USA
Tomoyo Sakata-Kato, Nicholas M. Brancucci, David Clarke, Maurice A. Itoe, Ping S. Lui, Amanda K. Lukens, Emily Lund, Elamaran Maybalan, Flaminia Catteruccia, Mathias Marty, and Dianne F. Wirth
Molecular Medicine Group, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Road, New Delhi, India
Arvind Sharma, Manmohan Sharma and Amit Sharma
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts, USA
Mika Maetani, Bennett K. Meyer and Stuart L. Schreiber
School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, California, USA
Victoria Corey and Elizabeth A. Winzeler
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts, USA
Emily R. Derbyshire and John C. Clardy
Department of Chemistry and Department of Molecular Genetics and Microbiology, Duke University, 124 Science Drive, Durham, North Carolina, USA
Emily R. Derbyshire
Department of Biochemistry and Microbiology, University of Victoria, 270 Petch Hall, Victoria, British Columbia, Canada
Gillian L. Dornan, Jacob A. McPhail and John E. Burke
Esquitis Institute for Drug Discovery, Griffith University, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, Australia
Sandra Duffy and Vicki M. Avery
Eisai Inc., 4 Corporate Drive, Andover, Massachusetts, USA
Sean Ackley, Branko Mitasev, Yvonne Van Gessel and Fabian Gusovsky
TropIQ Health Sciences, Geert Grooteplein 28, Huispost 268, Nijmegen, The Netherlands
Karin M.J. Coolen and Cohen J. Dechering
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA, USA
Sandra March and Sangeeta N. Bhatia
Eisai Co. Ltd, 5-1-3 Tokodai, Tsukuba, Ibaraki, Japan
Takashi Yoshinaga
Department of Parasitology, Center for Primate Biochemical Research, Rijswijk, The Netherlands
Anne-Marie Zeeman and Clemens HM Kocken






