College football odds, lines, spreads, predictions: Week 13 picks, best bets today

College football's Week 13 schedule matches the SEC's annual late-season schedule, when many teams face Group of Five opponents. While there are 14 SEC teams in action, the only four games you can pick for Week 13 college football are conference matchups. This is highlighted by Oklahoma vs. Missouri, a Top 25 matchup in which OU is a 7.5-point favorite. There's another ranked contest, and Oregon is a 10-point favorite over USC, according to the latest college football odds for Week 13.

Even though there are no elite matches, there are still some interesting games, many of which pit bitter rivals against each other. They include Tennessee vs. Florida (+4.5), UNC vs. Duke (-6.5), Texas vs. Arkansas (+9.5) and Miami vs. Virginia Tech (+17.5). It wouldn't be the worst thing to seek college football betting advice, given that something unexpected happens every Saturday. Before you lock in any Week 13 college football predictions, be sure to see the latest college football predictions for Week 13, based on SportsLine's proven model.

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The model simulates every FBS game 10,000 times. Since its inception, the company has generated over $2,000 in bet profits for $100 bettors on its top college football picks. Anyone who follows him American football betting poking around in bookmakers and further betting sites could see strong profits.

Now he turned his attention to the latest college football chances and week 13 American football betting lines on the spread, money line and over/under. Head here to see each selection..

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Best College Football Predictions for Week 13

One of the college football picks the model got in Week 13: Kansas State (+17.5, 52.5) ​​is ranked No. 13 Utah heading into Saturday's 4:00 pm ET kickoff. K-State's defense is one of the most opportunistic in the country, with 24 takeaways on the season and five in Saturday's win over Oklahoma State. Meanwhile, Utah has made just six takeaways in its last six games, and Utah can be sloppy at times as they have averaged seven penalties in their last four games. This contrasts with the disciplined unit led by Chris Klieman, as KSU ranks fifth in penalties (3.5) in the FBS. The margin superiority should allow the Wildcats to stay within that spread, with the model calling for a one-score game as KSU covers over 70% of the time. See other selections of models here.

Another prediction: No. 15 Georgia Tech (-2.5, 62.5) covers against Pitt in almost 60% of simulations Saturday at 7 p.m. ET. Pittsburgh faced its first top-15 squad in Notre Dame on Saturday, and the Panthers were embarrassed in a 22-point defeat. Pitt couldn't stop the Irish's rushing attack, giving up a season-high of 175 yards on the ground, and now Pittsburgh has to face a Yellow Jackets rushing attack that's top 10 in FBS in both yards per game and yards per carry. Not only that, but Georgia Tech's quarterback, Haynes King, also ranks fifth in the country in completion percentage as the Yellow Jackets offense should overwhelm the Panthers. In addition to Georgia Tech covering, the sims also have the Over hitting over 50% of the time. See which other picks the model likes here.

How to make college football picks for Week 13

The model has also made the call on who wins and covers in every FBS matchup in Week 13, and it's calling for multiple upsets in major games, including a pair of ranked teams outright losing to unranked foes. You can only get every pick for every game at SportsLine, and for a limited time you can use promo code CHAMPIONSHIP to get your first month at SportsLine for $1.

So what college football picks can you make with confidence, and which ranked squads go down? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception, and find out.

Week 13 college football odds for notable games

See full Week 13 college football picks, odds, predictions here
(odds subject to change)

Tuesday, Nov. 18

Akron vs. Bowling Green (-3, 46.5)

UMass vs. Ohio (-33.5, 51.5)

Western Michigan at Northern Illinois (+6.5, 38.5)

Wednesday, Nov. 19

Miami (OH) vs. Buffalo (+1.5, 39.5)

Central Michigan vs. Kent State (+9.5, 48.5)

Thursday, Nov. 20

Louisiana vs. Arkansas State (-2.5, 53.5)

Friday, Nov. 21

Florida State vs. NC State (+4.5, 61.5)

Hawaii vs. UNLV (-3, 64.5)

Saturday, Nov. 22

Miami vs. Virginia Tech (+17.5, 48.5)

Missouri vs. Oklahoma (-7.5, 42.5)

Arkansas vs. Texas (-9.5, 57.5)

Kentucky vs. Vanderbilt (-9.5, 53.5)

USC vs. Oregon (-10, 59.5)

Michigan vs. Maryland (+13.5, 45.5)

Kansas State vs. Utah (-17.5, 52.5)

Tennessee vs. Florida (+3.5, 57.5)

BYU vs. Cincinnati (+2.5, 54.5)

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