Notre Dame vs. Pittsburgh odds, line, picks: Week 12 picks from 10,000 simulations

10th place in the ranking Notre Dame Fighting Irish fight against 24th place in the ranking Pittsburgh Panthers in a key non-conference matchup on Saturday afternoon. Notre Dame beat Navy 49-10 last Saturday, and Pitt beat Stanford 35-20 on Nov. 1. The Fighting Irish (7-2), who have won seven straight games, are 2-1 on the road this season. The Panthers (7-2), who are tied for the Atlantic Coast Conference lead at 5-1, have won five straight and are 4-1 at home.

Kickoff at Acresure Stadium in Pittsburgh will be at noon ET. Notre Dame leads the all-time series 51-21-1, including a 28-11-1 advantage in games played in Pittsburgh. The Fighting Irish are 12.5-point favorites in the latest Notre Dame vs. Pittsburgh odds, and the over/under for total points scored is 54.5, according to the SportsLine consensus. Before you decide between Notre Dame and Pittsburgh, Check out the college football predictions with SportsLine's projection model.

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The model simulates every FBS game 10,000 times. Since its inception, the company has generated over $2,000 in bet profits for $100 bettors on its top college football picks. Anyone who follows him American football betting poking around in bookmakers and further betting sites could see strong profits.

Now the model has set its sights on Notre Dame vs Pittsburgh. You can visit SportsLine now to see the selection. Here's the FBS college football chances and trends for Pitt vs. Notre Dame:

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How to choose between Notre Dame and Pittsburgh

Model SportsLine moving on to the sum (54.5). The over has hit in six of Notre Dame's last 10 games, and the over has hit in seven of Pittsburgh's last 10 games. The model projects Fighting Irish quarterback C.J. Carr to throw for more than 250 yards and two touchdowns and running back Jeremiah Love to rush more than 15 times for nearly 100 yards and a score.

Panthers quarterback Mason Heinchel is projected to throw for more than 200 yards and more than one touchdown. The teams also combine for 58 points as the over is eliminated in more than 50% of simulations.

The model also says that one side of the spread hits almost 70% of the time. You can get this pick only at SportsLine.

So who will win Notre Dame vs. Pittsburgh, and which side of the spread hits nearly 70% of the time? Visit SportsLine now to find out which side of the Notre Dame vs. Pittsburgh game is worth jumping on, all thanks to an advanced model that has earned more than $2,000 on its FBS football predictions since its inception.and find out.