2026 NFL Wild Card Weekend picks, AI-generated score predictions, best bets

The 2026 NFL Wild Card weekend schedule includes two games on Saturday, three on Sunday and one Monday Night Football matchup between the teams Houston Texans And Pittsburgh Steelers. Monday's matchup pits quarterback C.J. Stroud and the Houston Texans against 21-year veteran Aaron Rodgers and the Pittsburgh Steelers. The Texans have a 3-point lead at DraftKings Sportsbook.

Other biggest spreads on Sunday include the Rams (-10.5) vs. the Panthers, the 49ers vs. the Eagles (-4.5) and the Chargers vs. the Patriots (-3.5). The tightest spreads in Wild Card Weekend include the Packers (-1.5) vs. the Bears and the Bills (-1.5) vs. the Jaguars. The top seeds, Seattle in the NFC and Denver in the AFC, take a week off.

Before making any NFL predictions for the 2026 Wild Card Weekend or predicting the NFL scores for these or other games, you should see NFL spread, over/under and moneyline predictions powered by SportsLine's self-learning AI..

AI predictions and rankings created by SportsLine's Data Science team using cutting-edge artificial intelligence and machine learning techniques are generated for every game. AI predictions are determined by statistically examining each team's historical data and then quantifying the strength of the opponent's defense by assigning a numerical value out of 100 called the match score. It constantly updates with the latest data available and can help you find the biggest row discrepancies. SportsLine's AI PickBot has selected more than 2,000 properties with 4.5 and 5 star ratings since the start of the 2023 season.

Weekend Wild Card NFL BettingSportsLine AI rated NFL odds and provided NFL betting options for all six games. You can view AI predictions for the 2026 NFL Wild Card Weekend schedule only here..

Best NFL AI Picks for 2026 Wild Card Weekend

After analyzing every Wild Card Weekend game, AI says the Steelers (+3, 39.5), who beat Baltimore in Week 18 to win the AFC North, are making up for some tough losses.

The Texans have won three of their last four games and the over has won four of the Steelers' last five games. Bet over 39.5 in the last one DraftKings Promo Codewhich offers bonus bets of $300 if your first bet wins.:

Pittsburgh has won four of the last six meetings with Houston and is expected to cover in a close game. The Steelers, who will get receiver DK Metcalf back from suspension, are looking to win their first playoff game since reaching the AFC Championship Game in 2016. Houston won the last meeting, 30-6, on Oct. 1, 2023. SportsLine AI rates the Steelers as a B money line pick and also predicts a 22-21 Texans win on average. See its other 2026 Wild Card Weekend football predictions and football picks at SportsLine, and bet the Steelers at DraftKings here:

How to make 2026 Wild Card Weekend NFL picks

In addition, the AI PickBot has generated three highly-coveted A picks for 2026 Wild Card Weekend. You need to see the AI's NFL picks before making any 2026 Wild Card Weekend NFL bets of your own. You can only see them at SportsLine.

Who wins and covers each 2026 Wild Card Weekend NFL game, and which A+ picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under and on the money line, all from the SportsLine AI that has nailed more than 2,000 highly-rated picks since the start of the 2023 season.

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